The effects of Modafinil on people with narcolepsy, sleep apnea, and shift work-related sleep disorder is known to be quite popular. Doctors generally prescribe this smart drug to such people to drive away excessive daytime drowsiness. But in healthy individuals too, this smart drug is seen to be practically effective just as well. In fact, in healthy people, this smart drug does not just help in driving away fatigue but also, bring about cognitive benefits.
Modafinil is the world’s first safe smart drug which is sold under different brand names. It is not just any supplement that you can avail in a supermarket store. In fact, these are clinically approved oral prescription medications which you can get only in a registered pharmacy. You can also avail Modafinil online from any online medical store of your choice. But make sure to get an approval from your doctor at the same time.
So, how exactly does Modafinil help in enhancing cognition in healthy individuals? Let us find out.
Modafinil is basically a wake-promoting agent that can drive away sleepiness and fatigue. It can do so by targeting the central nervous system and altering the actions of certain neurotransmitters. Let us understand the mechanism of Modafinil effects on the various neurotransmitters in detail-
Dopamine is a neurotransmitter that affects our mood, speech, and behavior. It also affects the sleep and wake cycle of individuals. Its availability in the brain can make one feel wakeful and active as the dopamine pathways activate. This also helps one to attain a particular level of focus.
The smart drug binds to the dopamine receptors and inhibits the reuptake of dopamine by the nerves. This increases the amount of extracellular dopamine in the nucleus accumbens.
Histamine is mainly found in the hypothalamus area and can transmit through the brain’s cortex region. This neurotransmitter plays a major role in our sleep and wake cycle. It helps in promoting a heightened sense of wakefulness in individuals.
Modafinil elevates the levels of histamine in these hypothalamus areas and cortex regions so that the subject feels more wakeful and energetic.
Serotonin is a mood-elevating neurotransmitter which plays a great role in influencing your motivational behavior. It is also good for enhancing memory power and concentration.
Modafinil has mood-elevating effects because of its ability to affect this neurotransmitter. It helps you feel motivated by increasing the amount of serotonin in the frontal cortex of the brain. This also helps you to fight excess anxiety levels. The effects of Modafinil on this neurotransmitter can help in the treatment of depression-like conditions.
This neurotransmitter is similar to adrenaline. Its main function is to mobilize the brain and the body for action. Other activities in the brain can also affect the levels of this neurotransmitter.
Modafinil helps trigger the production of this neurotransmitter in the hypothalamus and ventrolateral preoptic nucleus. At the time of inhibiting the reuptake of dopamine, this smart drug occupies the Norepinephrine transporter and inhibit its reuptake.
The right way to take Modafinil is to follow the doctor’s prescription instructions for its use. The ideally recommended dose is 200 mg for most of the first-time users.
Before you dose on Modafinil, you must undergo a proper check-up. If you have any health condition relating to cardiovascular problems, renal impairment or other such disorders, you should avoid taking this medication.
Note that, this smart drug is not an alternative to hold off sleep. In fact, it is only a wake-promoting agent that can give you a heightened sense of alertness and focus. Recreational use of Modafinil can be harmful to health. So, make sure to take this smart drug as per your doctor’s advice only.